Chiral recognition sites from carbonyldioxyglyceryl moiety by an alternative molecular imprinting

A novel candidate polymeric material bearing 5-membered cyclic carbonate moiety, poly[(2-oxo-1,3-dioxolan-4-yl)methyl methacrylate-co-acrylonitrile], was converted into a chiral recognition material by adopting Ac-d-Trp or Ac-l-Trp as a print molecule. The molecularly imprinted polymer showed chiral recognition ability, and the material imprinted by the d-isomer of Ac-Trp recognized the d-isomer in preference to the corresponding l-isomer and vice versa. The formation of the chiral recognition site was confirmed by the apparent adsorption isotherms of the molecularly imprinted materials.