کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10533027 961840 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Electrogenerated chemiluminescence of novel TiO2/CdS nanocomposites for sensitive assays of cancer cells
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Electrogenerated chemiluminescence of novel TiO2/CdS nanocomposites for sensitive assays of cancer cells
چکیده انگلیسی
A novel TiO2/CdS nanocomposite was prepared and used to fabricate an electrochemiluminescence (ECL) biosensor for the detection of cancer cells for the first time. The nanocomposite exhibited a strong cathodic ECL signal. Folic acid for targeting cell membranes was bound to a TiO2/CdS/3-aminopropyltriethoxysilane film, and specific recognition of folic acid to targeting cells was achieved, leading to a significant decrease in ECL intensity. The decrease in ECL signal was logarithmically related to the cell concentration in the range of 150-9600 cells mL-1. The ECL biosensor could provide a sensitive, selective, and convenient approach for early and accurate detection of cancer cells.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Analytical Biochemistry - Volume 442, Issue 1, 1 November 2013, Pages 34-39
نویسندگان
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