Synthesis and hyperthermia property of hydroxyapatite-ferrite hybrid particles by ultrasonic spray pyrolysis

► Biocompatible hybrid particles composed of hydroxyapatite (Ca10(PO4)6(OH)2, HAp) and ferrite (γ-Fe2O3 and Fe3O4) were synthesized using a two-step synthesis, which is comprised of co-precipitation and ultrasonic spray pyrolysis. ► Cross sectional TEM observation and X-ray diffraction revealed that synthesized hybrid particles showed two phases (HAp and ferrite), and the ferrite was coated with HAp. ► The saturation magnetization of ferrite in the HAp-ferrite hybrid was 32.49 emu/g. ► The increased temperature in the AC-magnetic field (370 kHz, 1.77 kA/m) was 9 °C with 3.4 g (the ferrite component was 1.0 g).