Motor activation in patients with Pantothenate-Kinase Associated Neurodegeneration: A functional magnetic resonance imaging study

As in other forms of dystonia, the increased activations of the motor system found in our patients could be related to the origin of the dystonic movements. Because in this condition the primary lesion affects the pallidum, a defect of the feed-back control mechanism between basal ganglia and cortex might be the responsible factor.