کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10747305 | 1048935 | 2011 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Immunohistochemical study of the principal pancreatic islet of the toadfish, Halobatrachus didactylus (Pisces: Batrachoididae)
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
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چکیده انگلیسی
The endocrine pancreas of the toadfish, Halobatrachus didactylus, consists of one large circular principal islet (Brockman body) located in the dorsal side or neck region of the gallbladder, along with various accessory islets of variable sizes and shapes, embedded in the exocrine tissue located within the digestive organs connecting mesenteries. Islet cells showed variable shapes, angular or fusiform, with long cytoplasmic processes, granular cytoplasm, and a large eccentric nucleus. Cells were found scattered or as aggregates or cords. Four primary endocrine cell types immunoreactive for glucagon (α cells), insulin (β cells), somatostatin (δ cells), and pancreatic polypeptide (F cells) were identified within the toadfish principal islet. The α, δ, and F cells were located both at the periphery and in the central regions, while β cells, which were the predominant type, were present only in the central core. α and δ cells were found in moderate frequencies, while F cells were the least abundant. Macroscopically, the Brockman body of H. didactylus is visible as a milky white nodule separated from the exocrine tissue. Its size, location, and ease of extraction suggest that H. didactylus is suitable as experimental subject for biochemical, immunological, and physiological studies of the endocrine pancreas including in vitro investigations of hormone production, storage, and release.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Acta Histochemica - Volume 113, Issue 3, May 2011, Pages 256-261
Journal: Acta Histochemica - Volume 113, Issue 3, May 2011, Pages 256-261
نویسندگان
José Luis Palazón-Fernández, Marta Peiro Suso, Juan Miguel Mancera, Carmen Sarasquete,