Inhibitory and antimicrobial activities of OGTI and HV-BBI peptides, fragments and analogs derived from amphibian skin

► OGTI do not display trypsin inhibitory activity as reported previously. ► OGTI exerts antimicrobial activity toward Staphylococcus epidermitis. ► HV-BBI can be the starting compound to design inhibitors of particular enzyme. ► HV-BBI and its analogs display dual properties: inhibitory and antibacterial.