Synthetic peptides from two Pf sporozoite invasion-associated proteins specifically interact with HeLa and HepG2 cells

► SIAP-1 and -2 peptides specifically interact with HeLa and HepG2 cell receptors. ► Proteoglycans mediate the specific binding of SIAP-1 and -2 HABPs. ► Antibodies against SIAP-1 and -2 peptides recognize the native proteins in P. falciparum sporozoites.