Peptidomic analysis of skin secretions demonstrates that the allopatric populations of Xenopus muelleri (Pipidae) are not conspecific

► Five antimicrobial peptides were isolated from skin secretions from Xenopus muelleri occupying a range in east Africa. ► Seven different antimicrobial peptides were isolated from skin secretions of X. muelleri occupying a non-contiguous range in west Africa. ► The western population of X. muelleri is more closely related to X. borealis than to X. muelleri from the eastern range consistent with a proposal to designate it as a separate species.