Angiotensin-(1-7) Mas-receptor deficiency decreases peroxisome proliferator-activated receptor gamma expression in adipocytes

► The lack of Ang-(1-7) action through Mas receptor increases the levels of serum NEFA. ► Mas-deficient mice present decreased response to the antilipolytic effect of insulin. ► Ang-(1-7) Mas receptor deficiency decreases lipogenic genes expression. ► Ang-(1-7) Mas receptor deficiency is accompanied by a decrease in PPARγ expression.