کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10836891 1066449 2005 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The mimetics of antiadhesive peptides as the inhibitors of Mycibacterium kansasii phagocytosis
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
The mimetics of antiadhesive peptides as the inhibitors of Mycibacterium kansasii phagocytosis
چکیده انگلیسی
The α-guanidino acids derived of 15 proteinaceous amino acids, ω-guanidino acids with gradually increased hydrocarbon chains, and amidinated dipeptides, were tested as the mimetics of antiadhesive peptides in Mycobacteria phagocytosis inhibition. The crystal structure of ω-guanidino acids used was determined by X-ray structural analysis. It follows from our experiments that the proper distance between guanidine and carboxyl groups of effector molecules is of decisive importance for their inhibitory activity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Peptides - Volume 26, Issue 9, September 2005, Pages 1543-1549
نویسندگان
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