کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10852743 1072000 2011 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The first subsequent entry biologic authorized for market in Canada: The story of Omnitrope, a recombinant human growth hormone
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوشیمی، ژنتیک و زیست شناسی مولکولی (عمومی)
پیش نمایش صفحه اول مقاله
The first subsequent entry biologic authorized for market in Canada: The story of Omnitrope, a recombinant human growth hormone
چکیده انگلیسی
Omnitrope is the first Subsequent Entry Biologic (SEB)/Similar Biotherapeutic Product (SBP) filed with Health Canada, for purposes of marketing. Health Canada is the home organization of the Regulatory Authority in Canada. As the first SEB to be filed for actual review, it presented unique challenges. While the principles for the review and approval of a SEB were laid out in a “fact sheet” there remained still a guidance to be drafted. The review of the submissions proceeded in parallel with the development of the guideline. This article will provide the details of how the final decision was arrived at and how that decision validated the principles underlying the guidance document, in the absence of direct regulations specifically addressing SEBs in Canada.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biologicals - Volume 39, Issue 5, September 2011, Pages 278-281
نویسندگان
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