Local inflammatory events induced by Bothrops atrox snake venom and the release of distinct classes of inflammatory mediators

► Bothrops atrox venom (BaV) induced local acute inflammatory events in mice. ► BaV increased vascular permeability and induced leukocyte influx into injection site. ► BaV-induced release of cytokines, CCL-2, eicosanoids and COX-2 expression.