Batroxase, a new metalloproteinase from B. atrox snake venom with strong fibrinolytic activity

► Batroxase is a weakly hemorrhagic metalloproteinase. ► Represent 1.2% (w/w) of the crude snake venom, pI 7.5 and molecular mass 22.9 kDa. ► Batroxase presented thrombolytic and fibrin(ogen)olytic activity. ► Batroxase was characterized as a PIb class SVMP. ► Clinical use as fibrinolytic agent for the treatment of coagulation disorders.