کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10880137 | 1076923 | 2011 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Developmental biology of the Brazilian 'Armed' spider Phoneutria nigriventer (Keyserling, 1891): Microanatomical and molecular analysis of the embryonic stages
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
بیوشیمی، ژنتیک و زیست شناسی مولکولی (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Developmental biology of the Brazilian 'Armed' spider Phoneutria nigriventer (Keyserling, 1891): Microanatomical and molecular analysis of the embryonic stages Developmental biology of the Brazilian 'Armed' spider Phoneutria nigriventer (Keyserling, 1891): Microanatomical and molecular analysis of the embryonic stages](/preview/png/10880137.png)
چکیده انگلیسی
Phoneutria (Ctenidae) is among the most dangerous venomous spiders in Brazil. Its venom is composed of a mixture of pharmacologically active components, some of which have been quite extensively studied due to their potentiality as models for new pharmaceutical drugs. Nevertheless, literature data on the venom-producing glands are very limited. In the present study, we follow the biological development of intra-cocoon stages of Phoneutria nigriventer spiders, mainly regarding the formation of the venomous apparatus and venom production. The results showed that the venom glands of Phoneutria are already present in the early 1st pre-larva stage. The venomous apparatus is completely formed in the larva, a stage that precedes the spider eclosion from the cocoon. At embryo stages, transcripts of a vertebrate-active neurotoxin (PhTx1) were shown to be present, as well as, unidentified venom proteins that were immunolabeled by anti-venom antibodies. It seems that venom toxins play roles in the protection and survival of those early developmental stages of Phoneutria spiders.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Toxicon - Volume 57, Issue 1, January 2011, Pages 19-27
Journal: Toxicon - Volume 57, Issue 1, January 2011, Pages 19-27
نویسندگان
Luciana Maria Silva, Consuelo Latorre Fortes-Dias, Priscila Pereira Schaffert, Ana Cristina Carvalho Botelho, Rafael Nacif-Pimenta, Maria Inácia Estevão-Costa, Marta do Nascimento Cordeiro, Paulo Filemon Paolucci Pimenta,