Phylogenetic analysis of serine proteases from Russell's viper (Daboia russelli siamensis) and Agkistrodon piscivorus leucostoma venom

► cDNAs of venom serine proteases from D. r. siamensis and A. p. leucostoma were cloned. ► The amino acid sequences of the cDNAs were analyzed by multiple sequence alignment. ► Phylogenetic trees were constructed to study their evolutionary relationship. ► KA/KS values suggested that accelerated evolution has occurred.