Reduction of infarct size by intravenous injection of uncultured adipose derived stromal cells in a rat model is dependent on the time point of application

► Stem cell therapy is a promising therapy for acute myocardial infarction. ► The stromal vascular fraction of adipose tissue contains adipose derived stem cells. ► Injection of SVF-cells and cultured ASCs 7 days post-AMI reduced infarct size. ► Intravenous delivery of SVF cells is saver than cultured ASCs. ► Injection of SVF cells 1 day post AMI does not significantly reduce infarctsize.