کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10908760 | 1087803 | 2014 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Validation of the revised International Prognostic Scoring System (IPSS-R) in patients with myelodysplastic syndrome: A multicenter study
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
تحقیقات سرطان
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چکیده انگلیسی
The revised IPSS (IPSS-R) was developed aiming at a better prognostication, taking into account patients treated with best supportive care. We herein validated this model on the basis of data from 1314 patients who received BSC only as well as patients who underwent induction chemotherapy (n = 214) or allogeneic transplantation (n = 167). We could demonstrate a clear distinction of the IPSS-R risk categories with regard to survival and risk of AML evolution in all patient cohorts. When comparing IPSS-R, IPSS, WHO prognostic scoring system (WPSS) and Duesseldorf score, the best results regarding the ability to predict survival were obtained by the IPSS-R.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Leukemia Research - Volume 38, Issue 1, January 2014, Pages 57-64
Journal: Leukemia Research - Volume 38, Issue 1, January 2014, Pages 57-64
نویسندگان
Judith Neukirchen, Michael Lauseker, Sabine Blum, Aristoteles Giagounidis, Michael Lübbert, Samuela Martino, Sergio Siragusa, Richard F. Schlenk, Uwe Platzbecker, Wolf-Karsten Hofmann, Katharina Götze, Giuseppe A. Palumbo, Silvana Magrin,