کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10909291 | 1087849 | 2011 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
NT-proBNP: A cardiac biomarker to assess prognosis in non-Hodgkin lymphoma
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
تحقیقات سرطان
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چکیده انگلیسی
NT-proBNP provides diagnostic and prognostic information in heart syndromes but its role in cancer has not yet been established. The prognostic value of NT-proBNP was prospectively studied in 104 non-Hodgkin lymphoma (NHL) patients treated with chemotherapy. Echocardiography and NT-proBNP were determined prior to treatment. In multivariate analysis, NT-proBNP â¥Â 900 pg/ml was the variable with higher risk of death (adjusted hazard ratio 11.1; 95% CI 3.8-32.9; P < 0.001). The C statistic for NT-proBNP â¥Â 900 pg/ml was significantly better than IPI score for prediction of survival. These findings suggest that NT-proBNP â¥Â 900 pg/ml could be considered a useful marker for risk assessment in NHL patients treated with chemotherapy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Leukemia Research - Volume 35, Issue 6, June 2011, Pages 715-720
Journal: Leukemia Research - Volume 35, Issue 6, June 2011, Pages 715-720
نویسندگان
Eva Gimeno, Miquel Gómez, Juan Ramón González, Josep ComÃn, Alberto Alvarez-Larrán, Blanca Sánchez-González, Lluis Molina, Eva Domingo-Domenech, Francesc Garcia-Pallarols, Carmen Pedro, Eugenia Abella, Carles Vilaplana, Silvia de Sanjosé,