کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10909815 | 1087941 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Cancer chemotherapy reduces plasma total antioxidant capacity in children with malignancies
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
تحقیقات سرطان
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Cancer chemotherapy reduces plasma total antioxidant capacity in children with malignancies Cancer chemotherapy reduces plasma total antioxidant capacity in children with malignancies](/preview/png/10909815.png)
چکیده انگلیسی
The sum of endogenous and food-derived antioxidants provides an estimate of the total antioxidant capacity (TAC) of the extracellular fluids, while corrected TAC (cTAC) is an estimation of the exogenously provided antioxidants. Similar values for TAC and cTAC were observed between cancer free children and children with malignancy at diagnosis. Antineoplastic treatment induced a significant decrease of TAC and cTAC during chemotherapy. Additionally to the dietary factors, this might be attributed to the antineoplastic drugs as shown by the significant increase of ROS after administration of chemotherapeutic agents both in vitro and in vivo. According to our preliminary results TAC and cTAC returned to normal after the end of therapy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Leukemia Research - Volume 29, Issue 1, January 2005, Pages 11-16
Journal: Leukemia Research - Volume 29, Issue 1, January 2005, Pages 11-16
نویسندگان
Maria Papageorgiou, Eftichia Stiakaki, Helen Dimitriou, Niki Malliaraki, George Notas, Elias Castanas, Maria Kalmanti,