کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10911846 1088393 2005 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Efficacy of the tyrosine kinase inhibitor gefitinib in a patient with metastatic small cell lung cancer
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Efficacy of the tyrosine kinase inhibitor gefitinib in a patient with metastatic small cell lung cancer
چکیده انگلیسی
Gefitinib (Iressa, ZD1839) is an orally active inhibitor selective for the epidermal growth factor receptor tyrosine kinase and has shown promise in the treatment of non-small cell lung cancer (NSCLC). There has been no report to date of the effect of gefitinib treatment in patients with small-cell lung cancer (SCLC). Here we report a case of metastatic SCLC that was successfully treated with gefitinib. This case is the first reported of objective clinical response after gefitinib treatment in a patient with SCLC. Our report suggests that treatment with gefitinib is a novel option for a subset of patients with SCLC.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Lung Cancer - Volume 48, Issue 1, April 2005, Pages 141-144
نویسندگان
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