Streptonigrin induces delayed chromosomal instability involving interstitial telomeric sequences in Chinese hamster ovary cells

► Streptonigrin induces chromosome damage in the progeny of CHO cells. ► CHO cells show increased number of telomeric signals 6 days after streptonigrin exposure. ► CHO cells show increased number of breaks at centromeric ITSs 6 days after streptonigrin exposure. ► Streptonigrin induces delayed instability of ITSs.