کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10940864 | 1095526 | 2015 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Batf3 deficiency is not critical for the generation of CD8α+ dendritic cells
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
بیولوژی سلول
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Recently, we have reported that CD8α+ DCs, rather than CD8+ T cells, are involved in the establishment and maintenance of HSV-1 latency in the trigeminal ganglia (TG) of ocularly infected mice. In the current study, we investigated whether similar results can be obtained using Batf3â/â mice that previously were reported to lack CD8α+ DCs. However, our results demonstrate that Batf3â/â mice, without any known infection, express CD8α+ DCs. Consequently, due to the presence of CD8α+ DCs, no differences were detected in the level of HSV-1 latency between Batf3â/â mice compared with wild type control mice.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Immunobiology - Volume 220, Issue 4, April 2015, Pages 518-524
Journal: Immunobiology - Volume 220, Issue 4, April 2015, Pages 518-524
نویسندگان
Kevin R. Mott, Hadi Maazi, Sariah J. Allen, Mandana Zandian, Harry Matundan, Yasamin N. Ghiasi, Behrooz G. Sharifi, David Underhill, Omid Akbari, Homayon Ghiasi,