کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10961344 | 1101549 | 2014 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Antithrombin: Could It be a Diagnostic and Prognostic Marker in Septic Neonatal Foals?
ترجمه فارسی عنوان
آنتی ترومبین: آیا می توان آن را یک نشانگر تشخیصی و پیش آگهی در نوزادان سپتیک نوزاد بود؟
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کلمات کلیدی
آنتی ترومبین، لانه نوزادان سپسیس، شوک سپتیک،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
چکیده انگلیسی
Antithrombin (AT) levels are lower in human neonates affected by sepsis and in nonsurvivors compared with survivors. The aims of this study were to evaluate AT profile in healthy newborn foals and its diagnostic and prognostic role in septic foals during the first week of life. Fifteen healthy foals and 35 septic foals were enrolled. Blood samples were collected from each healthy foal at 30Â minutes, 3 and 12Â hours from birth, daily from days 1-7, and at days 10 and 14. Blood was collected from each septic foal twice a day from admission to discharge or death. The AT analysis was performed by chromogenic method. Healthy foals showed decreasing levels of AT between 3Â hours and 2Â days, followed by an increasing trend. Septic foals did not show any difference during the period of observation, and no differences were found between healthy and septic age-matched foals. The analysis of AT activity on the day of admission in septic foals showed higher levels compared with healthy foals, in animals hospitalized at 12 and 24Â hours of age (P < .01). No differences were found at admission between foals affected by sepsis and that with septic shock. Nonsurviving foals showed significantly lower levels at 3 and 4Â days of age compared with surviving foals; when surviving and nonsurviving foals were compared independently by the age, nonsurviving foals showed significant (P < .05) lower levels 12Â hours after admission. In conclusion, AT seems to show neither a diagnostic nor a prognostic role in septic neonatal foals.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Equine Veterinary Science - Volume 34, Issue 10, October 2014, Pages 1211-1217
Journal: Journal of Equine Veterinary Science - Volume 34, Issue 10, October 2014, Pages 1211-1217
نویسندگان
Sara DVM, PhD, Carolina DVM, PhD, Dipl ECAR, Tiziana DVM, PhD, Alessandro DVM, PhD, Paola DVM, PhD, Maria Cristina DVM, PhD, Dipl ECAR,