Design, synthesis and pharmacological evaluation of N4,N6-disubstituted pyrimidine-4,6-diamine derivatives as potent EGFR inhibitors in non-small cell lung cancer

Design, synthesis and pharmacological evaluation of N4,N6-disubstituted pyrimidine-4,6-diamine derivatives as potent EGFR inhibitors in non-small cell lung cancer

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 157, 5 September 2018, Pages 1300-1325

Yuan Zhang, Handeng Lv, Lu Luo, Yong Xu, Yaqian Pan, Yuewu Wang, Han Lin, Jianhua Xiong, Ping Guo, Jinsan Zhang, Xiaokun Li, Faqing Ye,