کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
11015492 1783218 2018 34 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Elabela, a newly discovered APJ ligand: Similarities and differences with Apelin
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Elabela, a newly discovered APJ ligand: Similarities and differences with Apelin
چکیده انگلیسی
The Apelin/APJ system is involved in a wide range of biological functions. For a long time, Apelin was thought to be the only ligand for APJ. Recently, a new peptide that acts via APJ and has similar functions, called Elabela, was identified. Elabela has beneficial effects on body fluid homeostasis, cardiovascular health, and renal insufficiency, as well as potential benefits for metabolism and diabetes. In this review, the properties and biological functions of this new peptide are discussed in comparison with those of Apelin. Important areas for future study are also discussed, with the consideration that research on Apelin could guide future research on Elabela.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Peptides - Volume 109, November 2018, Pages 23-32
نویسندگان
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