کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
11024434 1701156 2018 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Transformation of biomanufacturing by single-use systems and technology
ترجمه فارسی عنوان
تبدیل محصولات زیستی با استفاده از سیستم های تک کاربره و تکنولوژی
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
چکیده انگلیسی
Biomanufacturing has been and continues to be transformed by the rapid innovation and adoption of single use technology (SUT). SUT has changed how bioprocesses are designed, scaled, operated, controlled, and the speed at which new technology can be incorporated into biomanufacturing. We are continually seeing advances in single use bioreactors, mixing vessels, harvest technology, and downstream bioprocess equipment. This transformation has not been limited to bioprocess equipment. In this contribution, a summary of how SUT is rapidly transforming bioprocesses and the facilities they operate in will be discussed, including SUT enabled bioprocess intensification through high cell density perfusion and continuous biomanufacturing processes. Examples of how SUT has opened up new approaches to achieving regulatory and bioprocess requirements resulting in simplified, less costly facilities to build and to operate will be presented.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Chemical Engineering - Volume 22, December 2018, Pages 62-70
نویسندگان
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