Method development for thermal ionization mass spectrometry in the frame of a biokinetic tracer study with enriched stable isotopes of zirconium

► Development of ID-TIMS for all stable Zr isotopes in several compositions at once. ► Optimization for trace amounts of Zr in human blood plasma and urine. ► Ionization enhancement by carbon coated rhenium single filaments. ► Multiple channel electron multipliers as detectors. ► Tracer detection limits below 1 ng ml−1.