کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1194562 1492332 2010 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Bioimaging of metals in brain tissue from micrometre to nanometre scale by laser ablation inductively coupled plasma mass spectrometry: State of the art and perspectives
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Bioimaging of metals in brain tissue from micrometre to nanometre scale by laser ablation inductively coupled plasma mass spectrometry: State of the art and perspectives
چکیده انگلیسی

Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) with multi-element capability is well established for the trace and ultratrace analysis of metals, metalloids and selected non-metals (such as C, P, S) in biological and clinical samples. Nowadays LA-ICP-MS is employed as a sensitive elemental mass spectrometric technique for the imaging of metals and non-metals in microtome thin tissue sections, especially for the determination of element concentrations at the trace and ultratrace level in selected small brain regions. This article discusses the state of the art of bioimaging of metals in thin brain tissue sections by LA-ICP-MS with spatial resolution at the micrometre scale and prospects for developing quantitative techniques at nanometre range.

The review discusses the quantitative bioimaging of metals in brain tissue by LA-ICPMS at the micrometre scale and prospects for techniques at nanometre range.Figure optionsDownload high-quality image (154 K)Download as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Mass Spectrometry - Volume 289, Issues 2–3, 15 January 2010, Pages 65–75
نویسندگان
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