کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1194827 1492346 2009 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Characterization of bis-carboxyethyl germanium sesquioxide and its complexes with amino acids using electrospray QqTOF mass spectrometry
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Characterization of bis-carboxyethyl germanium sesquioxide and its complexes with amino acids using electrospray QqTOF mass spectrometry
چکیده انگلیسی

This work deals with the application of electrospray ionization mass spectrometry (ESI-MS) with QqTOF analyzer for the characterization of Ge-132 complexes with different amino acids in aqueous solution with the emphasis on the determination of elemental composition. ESI mass spectra provide complementary structural information in both polarity modes. Some reaction products were suggested based on the interpretation of high resolution mass spectra. Moreover, the experimental isotopic distributions of ions were compared with theoretical calculated isotopic clusters. The superposition of many ion overlays was observed due to the wide isotopic distributions of studied polyisotopic complexes. The high resolution QqTOF analyzer enabled the discrimination of these ion signals differing at least by 0.12 mass units. The occurrence of overlaid signals from ions with smaller mass difference was successfully recognized based on the shift of isotopic distribution, and their elemental composition was verified using mass accuracies of non-overlaid isotopes at the borders of the isotopic cluster. Mass spectra obtained with ion trap and single quadrupole analyzers support QqTOF data.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Mass Spectrometry - Volume 280, Issues 1–3, 1 February 2009, Pages 198–203
نویسندگان
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