کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1226982 968338 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Desferrioxamine–cadmium as a ‘Trojan horse’ for the delivery of Cd to bacteria and fungi
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Desferrioxamine–cadmium as a ‘Trojan horse’ for the delivery of Cd to bacteria and fungi
چکیده انگلیسی

SummaryMolecules naturally designed for the acquisition of essential metals can be used as a shuttle to deliver toxic metal ions to target organisms. In this study, we describe for the first time the synthesis of a derivative of cadmium and desferrioxamine B, a bacterial siderophore. The new compound was characterized by elemental analysis, vibrational (infrared and Raman) spectroscopy, mass coupled thermal analyses and X-ray diffraction methods. Studies on the in vitro toxicity toward a fungus and two bacterial strains indicated that the coordination compound is more active against microrganisms than cadmium chloride on a Cd-concentration basis, indicating that desferrioxamine can work as a “Trojan horse” in the delivery of a toxic metal.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Trace Elements in Medicine and Biology - Volume 27, Issue 2, April 2013, Pages 103–108
نویسندگان
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