کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1226982 | 968338 | 2013 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Desferrioxamine–cadmium as a ‘Trojan horse’ for the delivery of Cd to bacteria and fungi
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
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چکیده انگلیسی
SummaryMolecules naturally designed for the acquisition of essential metals can be used as a shuttle to deliver toxic metal ions to target organisms. In this study, we describe for the first time the synthesis of a derivative of cadmium and desferrioxamine B, a bacterial siderophore. The new compound was characterized by elemental analysis, vibrational (infrared and Raman) spectroscopy, mass coupled thermal analyses and X-ray diffraction methods. Studies on the in vitro toxicity toward a fungus and two bacterial strains indicated that the coordination compound is more active against microrganisms than cadmium chloride on a Cd-concentration basis, indicating that desferrioxamine can work as a “Trojan horse” in the delivery of a toxic metal.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Trace Elements in Medicine and Biology - Volume 27, Issue 2, April 2013, Pages 103–108
Journal: Journal of Trace Elements in Medicine and Biology - Volume 27, Issue 2, April 2013, Pages 103–108
نویسندگان
Ana Luiza Costa Mattos, Vera Regina Leopoldo Constantino, Ricardo Alexandre Alves de Couto, Delia Manuela Luna Pinto, Telma Mary Kaneko, Breno Pannia Espósito,