Chemical vapor generation by coupling high-pressure liquid flow injection to high-resolution continuum source hydride generation atomic absorption spectrometry for determination of arsenic

• Innovative coupling of flow injection and high-resolution continuum source hydride generation atomic absorption spectrometry
• By changing the wavelengths between 190 nm and 800 nm, the online-detection method is adaptable to a wide range of elements.
• Coupling system provides hopeful prospects for chemical vapor generation
• Provides prospects of coupling of HPLC and high-resolution continuum source hydride generation atomic absorption spectrometry
• Determination of total arsenic content via alkine peroxdisulfate oxidation
• Overview and optimization of instrumental parameter

A coupled system for the online detection of total arsenic is presented consisting of a flow injection system (high pressure liquid (HPL) pump, injection loop of 250 μL) and high-resolution continuum source hydride generation atomic absorption spectrometry (HR-CS-HG-AAS).The system enables the continuous detection of volatile arsenic compounds and is adaptable for a wide range of elements.The analytical method was applied for the determination of total arsenic content in human urine. The limit of detection (LOD) with 0.09 μg/L (peak height) and the limit of quantification (LOQ) with 0.37 μg/L are comparable to standard methods.In this work, possibilities of arsenic determination with FI–HR-CS–HG–AAS have been explored. The online-coupling of a flow injection system with HR-CS–HG–AAS as an element-specific detector is a novel method for the detection and quantitative determination of arsenic and was reported for the first time in this paper.