کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1251523 | 970916 | 2006 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A Computational Study on Water-assisted Ammonolysis of N-Methyl β-Sultam1
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی (عمومی)
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The ring opening of β-sultam via an H2O-assisted ammonolysis process was studied by using Density Functional Theory(DFT) method at the B3LYP/6-31G* level as a further step in the theoretical investigation of the ammonolysis reaction of β-sultams. The calculated pathways are analogous to those previously described for the non-assisted ammonolysis reaction. Solvent effects were assessed by using the polarized continuum model (PCM) method. The results show that mode 1 and pathway a in channel II are the most favorable ones in both the cases. The energy barrier of the cleavage of CS bonds producing P1 is the highest among all the energy barriers. The presence of a solvent in the continuum model disfavors the reaction, whereas the participation of water in the ammonolysis reaction plays a positive role and reduces the active energy greatly. The relative energies of all the transition states in the assisted ammonolysis are 20-80 kJ/mol lower than those for the non-assisted reaction.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chemical Research in Chinese Universities - Volume 22, Issue 1, January 2006, Pages 94-98
Journal: Chemical Research in Chinese Universities - Volume 22, Issue 1, January 2006, Pages 94-98
نویسندگان
Mao-xia HE, Da-cheng FENG, Ling-juan YU, Zheng-ting CAI,