Synthesis, Characterization and Biological Activities of Novel Acrylamide Compounds

With dimethomorph and flumorph as the leading compounds, four novel acrylamide compounds with two types of structure were designed and synthesized by means of the method of “me too chemistry”. The target compounds were characterized by 1H NMR, IR, MS, and elemental analysis. The influences of solvent and raw material on the yield were investigated and optimum processing conditions were determined. The results of preliminary biological tests show that all those compounds exhibit certain antifungal activities.