کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1252967 971057 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Aptamer-based Electrochemical Biosensors for Highly Selective and Quantitative Detection of Adenosine
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Aptamer-based Electrochemical Biosensors for Highly Selective and Quantitative Detection of Adenosine
چکیده انگلیسی
A new adenosine biosensor based on aptamer probe is introduced in this article. An amino-labeled aptamer probe was immobilized on the gold electrode modified with an o-phenylenediamine electropolymerized film. When adenosine is bound specifically to the aptamer probe, the interface of the biosensor is changed, resulting in the decrement of the peak current. The response current is proportional to the amount of adenosine in sample. The used electrode can be easily regenerated in hot water. The proposed biosensor represents a linear response to adenosine over a concentration range of 1.0x10−7-1.0x10−4 mol/L with a detection limit of 1.0x10−8 mol/L. The presented biosensor exhibits a nice specificity towards adenosine. It offers a promising approach for adenosine assay due to its excellent electrochemical properties that are believed to be very attractive for electrochemical studies and electroanalytical applications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chemical Research in Chinese Universities - Volume 24, Issue 2, March 2008, Pages 138-142
نویسندگان
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