Tannic acid NPs – Synthesis and immobilization onto a solid surface in a one-step process and their antibacterial and anti-inflammatory properties

• Preparation of nanoparticles (NPs) of Tannic acid by applying ultrasonic waves.
• Immobilizing the NPs of tannic acid on cotton bandage to avoid its dissoluition.
• The tannic acid NPs coated on cotton show an anti-inflammatory effect.
• The bandage coated with TA NPs show antibacterial properties.

Tannic acid nanoparticles were synthesized from an aqueous solution without the use of stabilizers via a sonochemical process. In order to avoid the dissolution of the formed nanoparticles, the sonochemical reaction was performed in the presence of a cotton fabric: following their formation, the tannic acid nanoparticles were embedded into the cotton substrate in a one-step process. The bioactive properties of the tannic acid coated surface were examined towards the inhibition of myeloperoxidase and collagenase, two major enzymes related with inflammatory processes. In addition, the antibacterial activity of the tannic acid nanoparticles coated textiles was evaluated against Staphylococcus aureus and Pseudomonas aeruginosa.