Efficient one-pot three-component synthesis of N-(4-arylthiazol-2-yl) hydrazones in water under ultrasound irradiation

A highly efficient and facile one-pot three-component synthesis of N-(4-arylthiazol-2-yl) hydrazones was carried out in excellent yield without any catalyst in water under ultrasound irradiation.

► Water as solvent.
► Ultrasound increase yields.
► Better reaction times than conventional two-step method.
► Improved synthesis of N-(4-arylthiazol-2-yl) hydrazones.