Ultrasound assisted, ruthenium-exchanged FAU-Y zeolite catalyzed alkylation of indoles with epoxides under solvent free conditions

Ruthenium-exchanged FAU-Y zeolite (RuY) was used as a recyclable catalyst for regioselective ring-opening of epoxides with indoles under irradiation of sonic waves. It was found that a solvent free process, under the above mentioned conditions provides good yields of the desired 3-alkylated indole derivatives.

► A convenient method for the addition of indoles to epoxides is developed.
► Simultaneous application of sonic waves and RuY resulted in more efficiency.
► Regioselectivity toward secondary alcohol products was observed.
► Reusability of the catalyst and solvent free conditions are also, noticeable.