کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1265626 | 972232 | 2011 | 5 صفحه PDF | دانلود رایگان |

An efficient and direct procedure for the synthesis of amidoalkyl-2-naphthol derivatives has been described. The process employs a three-component cyclocondensation reaction in one-pot using β-naphthol, aromatic aldehyde and acetamide or benzamide in the presence of silica chloride accelerated by ultrasound giving the product in excellent yield in very short duration.
Research highlights
► Ultrasound assisted synthesis of amidoalkyl-2-naphthols.
► Aromatic aldehydes and 2-naphthol give o-quinone methides under sonic condition.
► Addition of amides to o-quinone methides give amidoalkyl-2-naphthols.
► Application of a heterogeneous and reusable catalyst – silica chloride under ultrasonic condition.
► Ultrasound enhances the rate and increases the yield of the products.
Journal: Ultrasonics Sonochemistry - Volume 18, Issue 2, March 2011, Pages 624–628