Metal free synthesis of homoallylic alcohols promoted by ultrasound

• Ultrasound promoted the allylation of aldehydes with potassium allyltrifluoroborates.
• A minimum amount of solvent was required, without any other catalyst or promoter.
• Products were obtained in high yields and short reaction times at room temperature.
• Products were obtained without the need of further purification.

The use of ultrasound irradiation to promote the allylation of aldehydes containing different functionalities with potassium allyltrifluoroborates is described. The method features the use of a minimum amount of acetone as solvent, without any other catalyst or promoter. The products were obtained in high yields, short reaction times, at room temperature and without the need of further purification.

Figure optionsDownload as PowerPoint slide