Synthesis, characterization and urease inhibitory activity of oxovanadium(V) complexes with similar Schiff bases

A series of structurally similar oxovanadium(V) complexes with analogous Schiff bases have been prepared and structurally characterized. The urease inhibitory activities of the complexes were investigated. The shorter the terminal groups of the Schiff base ligands are, the stronger the urease inhibitory activities of the oxovanadium(V) complexes.

Graphical AbstractA series of structurally similar oxovanadium(V) complexes with analogous Schiff bases have been prepared and structurally characterized. The urease inhibitory activities of the complexes were investigated.Figure optionsDownload as PowerPoint slideResearch Highlights
► A series of oxovanadium(V) complexes with Schiff bases have been synthesized.
► The complexes have been characterized by elemental analyses, IR spectra, and single crystal X-ray diffraction.
► The complexes show from moderate to strong urease inhibitory activity.
► The molecular docking study of the complexes with urease was performed.