Synthesis, spectroscopic and photophysical properties of novel styryldiazepinoporphyrazine

A novel porphyrazine possessing two styryl substituents conjugated with each of four diazepine rings was synthesized and characterized using UV–vis, MS MALDI and various NMR techniques. Solvent effects on the electronic absorption spectra of this porphyrazine were determined in protic and aprotic solvents. The changes observed in the electronic absorption spectra seem to result mainly from solvation as there was no correlation between the coordinating strength of the solvent and the red shift. Also the potential photosensitizing activity of this novel porphyrazine was evaluated by measuring its ability to generate singlet oxygen, which was found to reach the yield (ΦΔ) of 0.11 in DMF.

A novel porphyrazine possessing two styryl substituents conjugated with each of four diazepine rings was synthesized, characterized and subjected to photochemical studies. Potential photosensitizing activity of the novel porphyrazine was evaluated by measuring its ability to generate singlet oxygen, which was found to reach the yield of 0.11 in DMF.Figure optionsDownload as PowerPoint slideHighlights
► New symmetrical styryldiazepinoporphyrazine was synthesized and characterized.
► Porphyrazine was subjected to spectroscopic studies including solvatochromic effects.
► Potential photosensitizing activity of novel porphyrazine was evaluated.