کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1313533 | 1499312 | 2016 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Reaction of imidazole derivatives with trifluoromethylated arylacetylenes
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی معدنی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
• Nucleophilic addition of imidazoles to CF3-acetylenes leads to Z-isomers.
• Mixture of β- and α- vinylated imidazoles and benzimidazoles is formed.
• Not high polarization of the triple bond in CF3-acetylenes was revealed.
• Novel perspective multi-purpose building blocks were prepared.
The nucleophilic addition of imidazole derivatives to trifluoromethylated acetylenes was studied. Unpredictable regioselectivity of the reaction was observed to yield both β- and α-addition products. The reaction is 100% stereoselective to give the corresponding adducts as a Z-isomers only. The observed regioselectivity is discussed in terms of polarization of triple bond using experimental and calculated data.
Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Fluorine Chemistry - Volume 188, August 2016, Pages 157–163
Journal: Journal of Fluorine Chemistry - Volume 188, August 2016, Pages 157–163
نویسندگان
Boris A. Trofimov, Ludmila V. Andriyankova, Lina P. Nikitina, Kseniya V. Belyaeva, Anastasiya G. Mal’kina, Andrei V. Afonin, Igor A. Ushakov, Vladimir B. Kobychev, Vasily M. Muzalevskiy, Valentine G. Nenajdenko,