کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1313572 1499314 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Copper-mediated trifluoromethylation of diaryliodonium salts with difluoromethyltriflate
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی معدنی
پیش نمایش صفحه اول مقاله
Copper-mediated trifluoromethylation of diaryliodonium salts with difluoromethyltriflate
چکیده انگلیسی


• Trifluoromethylation of diaryliodonium salts was described.
• The trifluoromethylation was carried out at room temperature for 5 min.
• The reaction could be used for the radiosynthesis of [18F]trifluoromethylarenes.

The reaction of diaryliodonium salts with difluoromethyltriflate in the presence of TBAT and CuTC gave the corresponding trifluoromethylated arenes in moderate yields. Compared to other difluorocarbene-derived trifluoromethylation reactions, the current one proceeded at mild reaction conditions (room temperature) within short reaction time (5 min).

Trifluoromethylation of diaryliodonium salts with difluoromethyltriflate in the presence of TBAT and CuTC was carried out at room temperature for 5 min.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Fluorine Chemistry - Volume 186, June 2016, Pages 45–51
نویسندگان
, , ,