کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1313774 1499322 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis of trifluoromethylated compounds from alcohols via alkoxydiphenylphosphines
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی معدنی
پیش نمایش صفحه اول مقاله
Synthesis of trifluoromethylated compounds from alcohols via alkoxydiphenylphosphines
چکیده انگلیسی


• The trifluoromethylation of hydroxyl group in benzyl or allyl alcohols were investigated.
• Alkyloxydiphenylphosphine was formed as intermediate in this methodology.
• A plausible mechanism was proposed on the basis of experimental results.

The transformation of hydroxyl group in benzyl or allyl alcohols to trifluoromethyl was achieved via the reaction of the corresponding alkyloxydiphenylphosphine and CuCF3, generated in situ from methyl fluorosulfonyldifluoroacetate and CuI, under mild conditions. A plausible mechanism was proposed on the basis of experimental results.

The transformation of hydroxyl group in benzyl or allyl alcohols to trifluoromethyl could tolerate various functional groups and give the trifluoromethylated products via the corresponding alkyloxydiphenylphosphine under mild conditions.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Fluorine Chemistry - Volume 178, October 2015, Pages 254–259
نویسندگان
, , , ,