Regioselective addition reactions of 3-phenylsulfonyl-2-trifluoromethyl-1,3-butadiene with nucleophiles

► 3-Phenylsulfonyl-2-trifluoromethyl-1,3-butadiene underwent the regioselective nucleophilic addition reactions with heteroatom nucleophiles. ► The amine addition product of 3-phenylsulfonyl-2-trifluoromethyl-1,3-butadiene underwent the 5-endo-trig cyclization reaction to give the 4-phenylsulfonyl-3-trifluoromethylpyrrolidine derivatives. ► 4-Phenylsulfonyl-3-trifluoromethylpyrrolidine derivatives regenerated the 1,3-butadiene via amine elimination reaction.