کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1313944 | 1499324 | 2015 | 6 صفحه PDF | دانلود رایگان |
• 1,3-Dipolar cycloadditions of nitrile oxides and nitrones are reported.
• SF5-substituted alkynes are used in 1,3-dipolar cycloaddition reactions.
• Preparations of SF5-substituted isoxazoles and isoxazolines are reported.
A synthetic methodology utilizing 1,3-dipolar cycloadditions was developed for the preparation of pentafluorosulfanyl-substituted heterocycles using SF5-substituted arylacetylenes as key building block dipolarophiles. A group of 4-SF5-isoxazoles were prepared in moderate yields using in situ generated nitrile oxides, and 4-SF5-substituted isoxazolines were obtained when nitrones were used as the 1,3-dipole.
1,3-Dipolar cycloadditions of nitrile oxides and nitrones with SF5-substituted alkynes.Figure optionsDownload as PowerPoint slide
Journal: Journal of Fluorine Chemistry - Volume 176, August 2015, Pages 121–126