کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1314114 | 1499337 | 2014 | 5 صفحه PDF | دانلود رایگان |
• Palladium-catalyzed intramolecular cyclization of trifluoroacetimidoyl chlorides.
• CSp2–CSp2 bonds formation via C–H bond functionalization.
• The reaction afforded 6-trifluoromethyl-phenanthridines with good functional group tolerance.
Highly efficient approaches to obtain 6-trifluoromethyl-phenanthridine derivatives have been realized through the palladium-catalyzed intramolecular C–H bond functionalization of trifluoroacetimidoyl chlorides. The reaction allows the direct formation of CSp2–CSp2 bonds via C–H bond functionalization and rapid access to phenanthridine ring systems in moderate to high yields with good functional group tolerance.
Highly efficient approaches to obtain 6-trifluoromethyl-phenanthridine derivatives have been realized through the palladium-catalyzed intramolecular C−H bond functionalization of trifluoroacetimidoyl chlorides.Figure optionsDownload as PowerPoint slide
Journal: Journal of Fluorine Chemistry - Volume 163, July 2014, Pages 23–27