کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1314364 | 1499342 | 2014 | 5 صفحه PDF | دانلود رایگان |
• Tandem Knoevenagel–Michael reaction.
• CsF catalyzed.
• Xanthene synthesis.
• Excellent yields.
A simple, experimentally rapid and efficient CsF catalyzed tandem Knoevenagel–Michael reaction protocol is developed for the synthesis of a series of functionalized 9-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-enyl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one (1–7) by reacting dimedone with substituted salicylaldehydes. The use of CsF as a catalyst allowed reactions under moderate conditions and resulted in better yields.
An experimentally simple, rapid and efficient CsF catalyzed tandem Knoevenagel–Michael reaction protocol for the synthesis of series of functionalized 9-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-enyl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one have been reported by reacting dimedone with substituted salicylaldehyd.Figure optionsDownload as PowerPoint slide
Journal: Journal of Fluorine Chemistry - Volume 158, February 2014, Pages 1–5