Aggregation of fluorine-substituted pyridines

The influence of fluorine substituents on the crystallisation behaviour of pyridine was investigated by crystal structure determinations. The low melting compounds 2-fluoropyridine, 2,6-difluoropyridine and 2,4,6-trifluoropyridine were crystallised by in situ crystallisation directly on the single crystal X-ray diffractometer.

From T-shape to coplanar arrangement: fluorine substituents determine the crystal packings of the low melting fluoropyridines 2-fluoropyridine, 2,6-difluoropyridine and 2,4,6-trifluoropyridine.Figure optionsDownload as PowerPoint slide