کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1314502 | 975970 | 2011 | 8 صفحه PDF | دانلود رایگان |

Introduction of a polyfluoroalkyl group into aromatic compounds was achieved by Friedel-Crafts reaction using (1-chloro-1-hydroperfluoroalkyl) sulfides 1, and the subsequent desulfurizing–difluorination of the resulting product using IF5/Et3N-nHF. Perfluoroethyl, 1,1,2,2,3,3-hexafluoropropyl, and 1,1,2,2,3,3,4,4,5,5-decafluoropentyl groups were introduced to various aromatic compounds by this method. Selective perfluoroethylation of uracil at the 5-position was also performed.
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► Perfluoroethyl, hexafluoropropyl, and decafluoropentyl groups were introduced to various aromatic compounds.
► Starting material can be prepared from commercially available alcohols.
► Perfluoroethyl group was selectively introduced at the 5-position of uracil using our method.
Journal: Journal of Fluorine Chemistry - Volume 132, Issue 9, September 2011, Pages 579–586